Terence J O'Brien Selected Research

2',3'-dialdehyde ATP

1/2020

P2X7 receptor antagonism inhibits tumour growth in human high-grade gliomas.

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Terence J O'Brien Research Topics

Disease

96	Epilepsy (Aura) 06/2022 - 09/2003
75	Seizures (Absence Seizure) 05/2022 - 09/2003
21	Temporal Lobe Epilepsy 01/2022 - 01/2002
16	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2021 - 11/2009
14	Glioma (Gliomas) 07/2022 - 08/2012
14	Partial Epilepsies (Epilepsy, Partial) 06/2022 - 02/2005
13	Drug Resistant Epilepsy 03/2022 - 03/2004
13	Absence Epilepsy (Childhood Absence Epilepsy) 01/2019 - 02/2005
11	Status Epilepticus (Complex Partial Status Epilepticus) 11/2022 - 02/2005
11	Wounds and Injuries (Trauma) 01/2021 - 05/2014
10	Congenital Abnormalities (Deformity) 01/2021 - 09/2003
8	Autoimmune Diseases of the Nervous System 07/2022 - 01/2019
8	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 06/2014
8	Cognitive Dysfunction 12/2021 - 08/2009
8	Post-Traumatic Epilepsy (Epilepsy, Post Traumatic) 11/2019 - 01/2016
8	Schizophrenia (Dementia Praecox) 01/2019 - 08/2009
7	Idiopathic Generalized Epilepsy 01/2022 - 09/2010
7	Brain Injuries (Brain Injury) 01/2022 - 05/2015
6	Brain Concussion (Cerebral Concussion) 01/2022 - 12/2015
6	Neoplasms (Cancer) 01/2021 - 11/2008
6	Glioblastoma (Glioblastoma Multiforme) 01/2020 - 01/2015
6	Generalized Epilepsy 01/2020 - 02/2007
5	Neuroinflammatory Diseases 01/2021 - 12/2015
5	Psychotic Disorders (Schizoaffective Disorder) 01/2017 - 06/2012
5	Disease Progression 03/2016 - 06/2011
4	Encephalitis (Encephalitis, Rasmussen) 09/2022 - 01/2002
4	Sudden Unexpected Death in Epilepsy 01/2022 - 01/2019
4	Inflammation (Inflammations) 01/2022 - 04/2008
4	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 05/2014
4	Spinal Dysraphism (Spina Bifida) 01/2021 - 09/2013
4	Gliosis 01/2017 - 03/2007
3	Dementia (Dementias) 11/2022 - 01/2016
3	Stroke (Strokes) 10/2021 - 01/2019
3	Autism Spectrum Disorder 01/2021 - 09/2013
3	Multiple Trauma (Multiple Injuries) 01/2021 - 11/2017
3	Nervous System Diseases (Neurological Disorders) 01/2020 - 01/2012
3	Autistic Disorder (Autism) 07/2015 - 03/2013
2	Infections 01/2022 - 03/2021
2	Frontotemporal Dementia (Semantic Dementia) 01/2022 - 11/2020
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 08/2018
2	Ischemic Stroke 05/2021 - 11/2012
2	Spontaneous Abortion (Miscarriage) 01/2021 - 09/2003
2	Stillbirth 01/2021 - 09/2003
2	Dizziness (Lightheadedness) 10/2020 - 09/2015
2	Teratogenesis 10/2020 - 01/2013

Drug/Important Bio-Agent (IBA)

38	Biomarkers (Surrogate Marker)IBA 11/2022 - 06/2011
37	Pharmaceutical PreparationsIBA 01/2022 - 08/2005
29	Anticonvulsants (Antiepileptic Drugs)IBA 11/2021 - 09/2003
20	Valproic Acid (Depakote)FDA LinkGeneric 01/2021 - 09/2003
15	Proteins (Proteins, Gene)FDA Link 11/2022 - 11/2008
15	Carbamazepine (Tegretol)FDA LinkGeneric 01/2021 - 09/2003
12	Glutamic Acid (Glutamate)FDA Link 10/2021 - 08/2012
10	Selenic AcidIBA 01/2022 - 03/2012
10	salicylhydroxamic acid (SHAM)IBA 01/2021 - 05/2014
9	Kainic Acid (Kainate)IBA 11/2021 - 10/2008
8	Immunoglobulin E (IgE)IBA 01/2022 - 01/2009
7	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 07/2022 - 08/2009
7	T-Type Calcium Channels (T-Type Calcium Channel)IBA 11/2019 - 01/2009
6	Levetiracetam (Keppra)FDA LinkGeneric 01/2022 - 12/2012
6	Biological ProductsIBA 01/2020 - 01/2008
6	Neuropeptide YIBA 01/2018 - 02/2005
5	perampanelIBA 01/2022 - 09/2015
4	AntibodiesIBA 05/2022 - 01/2020
4	EnzymesIBA 01/2021 - 01/2016
4	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2021 - 05/2015
4	gamma-Aminobutyric Acid (GABA)IBA 01/2020 - 11/2006
4	CytokinesIBA 01/2020 - 05/2014
4	Messenger RNA (mRNA)IBA 01/2018 - 10/2008
3	Triglycerides (Triacylglycerol)IBA 11/2022 - 03/2019
3	Leucine (L-Leucine)FDA Link 07/2022 - 01/2020
3	Aminobutyrates (Aminobutyric Acid)IBA 07/2022 - 08/2013
3	AntioxidantsIBA 01/2022 - 12/2015
3	Amyloid (Amyloid Fibrils)IBA 12/2021 - 01/2015
3	Lacosamide FDA Link 10/2020 - 07/2014
3	HMGB1 Protein (HMG1)IBA 01/2020 - 01/2019
3	Z944IBA 11/2019 - 02/2012
3	Ion Channels (Ion Channel)IBA 01/2019 - 01/2014
3	Peptides (Polypeptides)IBA 01/2018 - 10/2009
3	Antidepressive Agents (Antidepressants)IBA 01/2018 - 03/2014
3	Phenytoin (Dilantin)FDA LinkGeneric 01/2018 - 09/2003
3	Ketamine FDA LinkGeneric 01/2017 - 08/2009
3	Ethosuximide (Zarontin)FDA LinkGeneric 01/2015 - 02/2012
3	GABA-A Receptors (GABA(A) Receptor)IBA 01/2014 - 11/2006
2	AutoantibodiesIBA 09/2022 - 05/2022
2	AcidsIBA 01/2022 - 01/2013
2	Blood Proteins (Serum Proteins)IBA 01/2022 - 10/2019
2	LipopolysaccharidesIBA 01/2022 - 03/2021
2	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2022 - 08/2018
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2021 - 06/2008
2	Topiramate (Topamax)FDA LinkGeneric 01/2021 - 10/2020
2	Phosphotransferases (Kinase)IBA 01/2021 - 09/2011
2	Purinergic P2X7 ReceptorsIBA 01/2021 - 01/2020
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 07/2015
2	Glutathione (Reduced Glutathione)IBA 12/2020 - 01/2020

Therapy/Procedure

44	Therapeutics 11/2022 - 11/2008
10	Electrodes (Electrode) 02/2021 - 01/2004
2	Wearable Electronic Devices 01/2022 - 01/2022
2	Ketogenic Diet 10/2021 - 11/2020
2	Stents 02/2021 - 01/2016
2	Induced Abortion (Induced Abortions) 01/2021 - 09/2003